Gynazole•1® (Butoconazole Nitrate Vaginal Cream USP, 2%)
is a prescription vaginal cream used to treat yeast infections in non-pregnant women.
Important Safety Information for Gynazole•1 (Butoconazole Nitrate Vaginal Cream USP, 2%)
You should not use Gynazole•1 if you have had an allergic reaction to butoconazole or
other ingredients in this cream.
Gynazole•1 contains mineral oil. Mineral oil may weaken latex or rubber products such as
condoms or vaginal contraceptive diaphragms. Due to this, the use of these contraceptives
is not recommended during Gynazole•1 treatment or for 3 days following treatment. During
this time period, condoms may not work reliably to prevent pregnancy or to protect against
HIV and other sexually transmitted diseases.
The most common side effects of Gynazole•1 are vulvar/vaginal burning, itching, soreness and
swelling, and pelvic or abdominal pain or cramping.
Be sure to talk to your doctor if your yeast infection does not get better or you experience
frequent yeast infections. Frequent yeast infections, especially those that are difficult
to treat, may be caused by another more serious health problem, like a weakened immune system.
To report negative side effects, contact Ther-Rx Corporation at 1-877-567-7676 or the FDA at 1-800-FDA-1088 or